UC San Diego

Ackerman Lab

Molecular mechanisms underlying neurodegeneration and CNS development

UC San Diego

Alexandrov Lab

Understanding the molecular processes that lead to cancer

UC San Diego

Antal Lab

Understanding molecular mechanisms that drive cancer

UC San Diego

Brown Lab

How G-protein signaling pathways regulate cell growth and inflammation and drive dysfunction in cancer and cardiac disease

UC San Diego

Budin Lab

How lipids act to shape cells and their membrane-bound signaling networks

UC San Diego

Burkart Lab

Drug discovery and development; RNA processing

UC San Diego

Chen Lab

Cellular and molecular mechanism underlying Alzheimer's disease and related neurodegeneration; Holistic regulation of neurodegeneration

Sanford Burnham Prebys

Commisso Lab

Signaling pathways that regulate metabolic stress tolerance in cancer

UC San Diego

Crews Lab

Cellular and Molecular signaling mechanisms that drive multiple myeloma stem cell activity and disease regeneration

UC San Diego

Daneman Lab

Cellular and molecular mechanisms that regulate the blood-brain barrier in health and disease

UC San Diego

Dennis Lab

Mechanism of the Phospholipase A Superfamily in Initiating Lipid Cell Signaling in Inflammation

UC San Diego

Desai Lab

Mechanisms ensuring accurate genome inheritance during cell division and their dysregulation/targeting in cancer

UC San Diego

Devaraj Lab

How can we manipulate lipid signaling processes in artificial and living cells

UC San Diego

Dore Lab

Molecular mechanisms underlying synaptic weakening and resilience in the context of Alzheimer's disease

Scripps Research Institute

Encalada Lab

Molecular mechanisms of neuronal endolysosomal trafficking in health and in neurodegeneration.

The Salk Institute

Engle Lab

Therapeutic interception of aberrant glycosylation in pancreatic disease

UC San Diego

Esko Lab

Signaling through glycan binding proteins that leads to cancer

The Salk Institute

Evans Lab

System approaches to map signaling networks impacting organismal health and disease

UC San Diego

Feng Lab

Deciphering the anti-oncogenic effects of oncoproteins in liver cancer

UC San Diego

Ferguson Lab

Chemical biology approaches to interrogating disease signaling in cancer and neurodegeneration

UC San Diego

Furnari Lab

Deciphering and targeting signaling networks in the etiology of brain cancer

UC San Diego

Ginsberg Lab

The Ginsberg Lab studies bi-directional transmembrane signaling by integrin adhesion receptors using biochemistry, cell biology, and forward and reverse genetics

UC San Diego

Gonzalez Lab

Studying bacterial pathogenesis, host responses to infection, and the impact of the microbiome on health and disease

UC San Diego

Gustafsson Lab

Regulation of mitochondrial morphology, function and turnover in cardiac homeostasis and heart failure

UC San Diego

Gutkind Lab

Translating our scientific discoveries into novel precision treatment options and immunotherapies to prevent and treat cancer

UC San Diego

Hamilton Lab

Genetic architectures that promote robust development in noisy signaling environments

UC San Diego

Handel Lab

Structure and signaling mechanisms of G protein-coupled and atypical chemokine receptors

UC San Diego

Hangauer Lab

Cancer, mutagenesis, apoptosis, immunotherapy, ferroptosis

UC San Diego

Hao Lab

Probing and engineering single-cell aging trajectories using systems and synthetic biology approaches

The Salk Institute

Hargreaves Lab

Understanding the role of SWI/SNF chromatin remodeling complexes in cancer and immunity

San Diego State University

Haricharan Lab

Understanding the somatic molecular biology of cancer through the lens of patient characteristics

UC San Diego

Hnasko Lab

Neural circuits & behavior, neurotransmitter co-release, drug addiction, Parkinson’s disease

UC San Diego

Hook Lab

Cell signaling via neurotransmitters, exosomes, and lysosomal leakage in health and neurological diseases

UC San Diego

Hui Lab

Mechanistic dissection of immune checkpoint receptors

The Salk Institute

Hunter Lab

Targeting protein histidine phosphorylation in pancreatic cancer, breast cancer and neuroblastoma

San Diego State University

Huxford Lab

Structure and mechanism of cellular factors that control transcription factor NF-kappaB activity

UC San Diego

Insel Lab

GPCR signaling, expression and roles in cellular function related to health and disease

UC San Diego

Jiang Lab

Double-stranded RNA induced inflammation signaling in leukemia initiating cells and hematopoietic stem cells by deciphering mechanisms of RNA editing dysregulation in pediatric leukemia

UC San Diego

Joiner Lab

Regulation of neurotransmitter signaling and the sleep/wake cycle in health and disease

UC San Diego

Karin Lab

Inflammation and cancer

Sanford Burnham Prebys

Kaufman Lab

The mechanisms by which protein misfolding in the endoplasmic reticulum cause human disease

UC San Diego

Kufareva Lab

Computational structural and systems pharmacology of GPCRs

UC San Diego

Li Lab

Growth factor and nuclear hormone control of hematopoietic stem and progenitor cell proliferation

UC San Diego

Identifying and targeting signals that drive tumor progression and drug resistance in pancreatic and appendiceal cancers

UC San Diego

Manor Lab

Cellular and molecular mechanisms underlying organelle dynamics in health and disease

UC San Diego

McCammon Lab

Development and application of computational methods to simulate molecular systems involved in signaling

UC San Diego

Meharena Lab

Developmental and cognitive genomics in neurological disorders

UC San Diego

Mendiola Lab

Decoding mechanisms of brain innate immune cell dysfunction in neurological diseases

San Diego State University

Monkkonen Lab

Functions of autophagy in the tumor microenvironment and intracellular signaling

The Salk Institute

Montminy Lab

Transcriptional control of glucose metabolism by phosphorylation-dependent activators

UC San Diego

Muotri Lab

Brain organogenesis using stem cells and neural signaling during development and evolution

La Jolla Institute for Immunology

Myers Lab

Signaling pathway crosstalk and post-translational mechanisms controlling cell fate decisions

UC San Diego

Newton Lab

Protein phosphorylation and deregulated signaling in cancer and neurodegeneration

UC San Diego

Novick Lab

The role of Rab GTPase networks in the regulation of vesicular traffic, the structure/inheritance of the endoplasmic reticulum, and the mechanism of ER-phagy

UC San Diego

Obara Lab

Directly visualizing individual signaling events with advanced microscopy techniques

Sanford Burnham Prebys

Pasquale Lab

Eph receptor tyrosine kinase signaling and targeting strategies

UC San Diego

Patrick Lab

Glutamate receptor trafficking and turnover at CNS synapses in health and disease

UC San Diego

Pekkurnaz Lab

Mechanisms regulating neuronal metabolic homeostasis and mitochondria in health and diseases

UC San Diego

Pillus Lab

Probing aging and epigenetics through the lenses of metabolism and chromatin biology

UC San Diego

Rangamani Lab

Computational systems biology and biophysics to generate predictions about spatio-temporal dynamics of signaling molecules

UC San Diego

Reck-Peterson Lab

Molecular mechanisms of intracellular transport in health and disease

Sanford Burnham Prebys

Ronai Lab

Mapping rewired signaling in cancer

The Salk Institute

Saghatelian Lab

Discovery and characterization of biologically active lipids and microproteins in health and disease

UC San Diego

Saltiel Lab

Molecular mechanisms governing the regulation of metabolism

UC San Diego

Understanding the interface between metabolic adaptation and signal transduction in macrophage immune functions

UC San Diego

Schlaepfer Lab

Targeting chemtherapy resistance and immune evasion pathways in ovarian cancer.

UC San Diego

Schoeneberg Lab

4D cell biology using advanced microscopy, stem cells, and machine learning

UC San Diego

Schroeder Lab

Molecular mechanisms by which plants respond to and mount resistance to environmental stresses

UC San Diego

Shaner Lab

Engineering and applying genetically encoded optical probes and actuators for live cell microscopy

The Salk Institute

Shaw Lab

How cells rewire growth and metabolism in nutrient-deprived conditions

UC San Diego

Molecular mechanisms underlying drug sensitivity and resistance in cancer

San Diego State University

Sohl Lab

The kinetic, structural, and cellular consequences of enzyme mutations that drive cancer

UC San Diego

Spitzer Lab

Brain plasticity and neurotransmitter switching

UC San Diego

Sunahara Lab

Understanding the structural and functional basis for hormone and drug modulation of G protein-coupled receptors

UC San Diego

Taylor Lab

Structure and function of protein kinases

The Salk Institute

Towers Lab

Targeting canonical and non-canonical mechanisms of autophagy and mitophagy in cancer cells

UC San Diego

Trejo Lab

Cell signaling in vascular inflammation and cancer

UC San Diego

Villa Lab

Development and application of cryo-electron tomography to study various cellular processes including LRRK2 in Parkinson's disease

UC San Diego

Willert Lab

The role of WNT signaling in development and disease

UC San Diego

Yaksh Lab

Neuraxial cell signaling in pain states secondary to tissue and nerve injury

UC San Diego

Yang Lab

Cell signaling and communication in tumor metastasis

UC San Diego

Zage Lab

Identifying novel therapeutic targets and developing new treatment approaches for pediatric solid tumors

UC San Diego

Zhang Lab

Spatiotemporal regulation of cell signaling in health and disease

UC San Diego

Zhou Lab

Deciphering signaling mechanisms that prevent chromosomal rearrangements and aneuploidy